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Figure 1 | Breast Cancer Research

Figure 1

From: Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2mutation carriers

Figure 1

BRCA2 plot of relative risk for rs3825977 and rs7166081 at the SMAD3 locus. BRCA2 plots of study group-specific relative risk (RR) for rs3825977 and rs7166081 at the SMAD3 locus. Study groups with 70 or more carriers and tests of heterogeneity are shown for (a) rs3825977 (overall RR (95% confidence interval (CI)) = 1.20 (1.03, 1.40), Ptrend = 0.018) and (b) rs7166081 (overall RR (95% CI) = 1.25 (1.07, 1.45), Ptrend = 0.004). OR, odds ratio.

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