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Table 2 Logistic regression analysis of the association between cystatin M loss and the losses of ER, PR, and HER4 in IBCs (N = 175)

From: Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer

 

OR

95% CI

P-value

Univariate1

   

   ER-negative

2.20

1.19 to 4.06

0.02

   PR-negative

2.41

1.32 to 4.39

0.007

   HER4-negative

3.09

1.44 to 6.62

0.003

Multivariate2

   

   Triple-negative

3.57

1.28 to 9.98

0.01

  1. 1 Reference was a group with expression of each protein. 2 Age was controlled in multivariate analysis, and other subtypes with expression of either ER, PR, or HER4 was used as a reference. Triple-negative, the losses of ER, PR, and HER4; ER, estrogen receptor; PR, progesterone receptor; OR, odds ratio; CI, confidence interval.