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Figure 1 | Breast Cancer Research

Figure 1

From: Cystatin M loss is associated with the losses of estrogen receptor, progesterone receptor, and HER4 in invasive breast cancer

Figure 1

Representative immunohistochemical statinings of ER, PR, HER2, HER4, and cystatin M in DCIS and IBC lesions. The positive (upper row) and negative (lower row) immunostainings for cystatin M, ER, PR, HER2, and HER4 are shown in DCISs and IBCs. Most cells in the upper row of DCIS and IBC lesions show strong nuclear reactivity for ER and PR, strong membrane reactivity for HER2, and strong cytoplasmic staining for HER4 and cystatin M. Magnification × 400.

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