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Table 3 Absolute riska to develop breast cancer in specific age intervals for cancer-free 40-year-old women by subtypeb and race/ethnicityc

From: Lifetime risks of specific breast cancer subtypes among women in four racial/ethnic groups

  Luminalb, d HER2-positiveb, d Triple-negativeb, d All subtypes
Race/Ethnicity Percentage (95% CI) Percentage (95% CI) Percentage (95% CI) Percentage (95% CI)
White, age 40     
   To age 50 0.87 (0.84, 0.90) 0.27 (0.25, 0.29) 0.17 (0.16, 0.19) 1.57 (1.52, 1.61)
   To age 70 4.54 (4.45, 4.63) 1.13 (1.09, 1.18) 0.76 (0.72, 0.79) 7.78 (7.67, 7.90)
   To end of life 8.00 (7.87, 8.14) 1.74 (1.68, 1.80) 1.19 (1.14, 1.24) 13.6 (13.5, 13.8)
Black, age 40     
   To age 50 0.59 (0.52, 0.66) 0.31 (0.26, 0.37) 0.34 (0.29, 0.40) 1.51 (1.40, 1.63)
   To age 70 2.83 (2.63, 3.03) 1.19 (1.07, 1.33) 1.31 (1.18, 1.45) 6.49 (6.02, 6.80)
   To end of life 4.55 (4.35, 4.76) 1.73 (1.55, 1.92) 1.91 (1.73, 2.11) 10.7 (10.3, 11.2)
Hispanic, age 40     
   To age 50 0.49 (0.46, 0.52) 0.23 (0.21, 0.25) 0.16 (0.14, 0.17) 1.07 (1.03, 1.12)
   To age 70 2.49 (2.38, 2.59) 0.94 (0.88, 1.01) 0.65 (0.60, 0.71) 4.99 (4.85, 5.14)
   To end of life 4.79 (4.59, 5.00) 1.50 (1.39, 1.61) 0.98 (0.90, 1.07) 8.83 (8.56, 9.11)
Asian, age 40     
   To age 50 0.71 (0.66, 0.77) 0.34 (0.30, 0.38) 0.10 (0.08, 0.12) 1.41 (1.34, 1.49)
   To age 70 2.81 (2.68, 2.95) 1.28 (1.19, 1.37) 0.45 (0.40, 0.51) 5.67 (5.47, 5.87)
   To end of life 4.92 (4.66, 5.20) 1.70 (1.66, 1.97) 0.72 (0.63, 0.84) 9.68 (9.31, 10.1)
All races, age 40     
   To age 50 0.72 (0.70, 0.74) 0.27 (0.26, 0.28) 0.17 (0.16, 0.18) 1.41 (1.38, 1.44)
   To age 70 3.72 (3.66, 3.78) 1.12 (1.08, 1.15) 0.73 (0.70, 0.76) 6.83 (6.75, 6.91)
   To end of life 6.74 (6.64, 6.84) 1.70 (1.66, 1.75) 1.14 (1.10, 1.18) 12.1 (12.0, 12.3)
  1. aRisk is conditioned on never having had breast cancer previously. bSubtypes were defined by expression of estrogen receptor (ER), progesterone receptor (PR), and Her2/neu (HER2): luminal (ER- or PR-positive or both and HER2-negative), HER2-positive (ER- and PR-positive or -negative and HER2-positive), and triple-negative (ER-negative, PR-negative, and HER2-negative). cRacial/ethnic categories are mutually exclusive and include white (non-Hispanic [NH]), black (NH), Hispanic, and Asian (NH, includes Pacific Islander). dExcludes 7,737 cases (5,069 whites, 505 blacks, 1,262 Hispanics, and 901 Asians) for whom ER, PR, and/or HER2 were not tested or for whom results were borderline, missing, or unknown; these cases are included in the 'All subtypes' category. CI, confidence interval.