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Table 2 Geometric mean (95% confidence interval) hormone concentrations in prediagnostic serum from casesa and matched controls

From: Prospective case-control study of premenopausal serum estradiol and testosterone levels and breast cancer risk

 

Cases

Controls

 
 

n

Mean

95% CI

n

Mean

95% CI

P b

Estradiol, pg/ml

98

85.8

72.5-101.5

168

80.3

70.5-91.6

0.62

Bioavailable estradiol, pg/ml

98

49.9

42.1-59.0

168

45.7

40.2-51.9

0.46

Testosterone, ng/dl

98

28.1

26.2-30.1

168

24.7

23.3-26.1

0.005

Bioavailable testosterone, ng/dl

98

11.8

10.8-12.8

168

10.1

9.5-10.7

0.002

SHBG, nmol/L

98

55.2

50.4-60.4

168

57.7

53.7-62.0

0.34

  1. All variables are continuous. CI, confidence interval; SHBG, sex hormone-binding globulin. aMean (± SD) time from blood collection to diagnosis was 14.0 ± 6.6 years. bP values (two-sided) were calculated by using conditional logistic regression with log-transformed hormone and SHBG levels entered as a linear term to test for trend by using a Wald test.