Variable | ER+ | ER- | ||||
---|---|---|---|---|---|---|
 | Loss of wt BRCA1N(%) | No loss of wt BRCA1N(%) | P-value | Loss of wt BRCA1N(%) | No loss of wt BRCA1 N(%) | P-value |
Cytokeratins | Â | Â | Â | Â | Â | Â |
CK5/6 | (31) | (7) | 0.164 | (27) | (4) | 0.010 |
   Positive | 9 (29.0) | 0 |  | 20 (74.1) | 0 |  |
   Negative | 22 (71.0) | 7 (100) |  | 7 (25.9) | 4 (100) |  |
CK7/8 | (31) | (8) | --- | (28) | (4) | 1.0 |
   Positive | 31 (100) | 8 (100) |  | 25 (89.3) | 4 (100) |  |
   Negative | 0 | 0 |  | 3 (10.7) | 0 |  |
CK14 | (31) | (6) | 0.566 | (27) | (3) | 0.054 |
   Positive | 5 (16.1) | 0 |  | 18 (66.7) | 0 |  |
   Negative | 26 (83.9) | 6 (100) |  | 9 (33.3) | 3(100) |  |
CK5/6 or CK14 | (33) | (8) | 0.083 | (27) | (4) | 0.001* |
   Positive | 11 (33.3) | 0 |  | 24 (88.9) | 0 |  |
   Negative | 22 (66.7) | 8 (100) |  | 3 (11.1) | 4 (100) |  |
CK 18 | (32) | (7) | ---- | (27) | (4) | 1.00 |
   Positive | 32 (100) | 7 (100) |  | 26 (96.3) | 4 (100) |  |
   Negative | 0 | 0 |  | 1 (3.7) | 0 |  |
CK19 | (33) | (6) | ---- | (28) | (4) | 0.125 |
   Positive | 33 (100) | 6 (100) |  | 28 (100) | 3 (75) |  |
   Negative | 0 | 0 |  | 0 | 1 (25) |  |
EGFR | (30) | (7) | 0.560 | (26) | (4) | 0.360 |
   Positive | 5 (16.7) | 0 |  | 24 (92.3) | 3(75) |  |
   Negative | 25 (83.3) | 7 (100) |  | 2 (7.7) | 1 (25) |  |
CK5/6 and/or CK14 and/or EGFR | (33) | (8) | 0.083 | (28) | (4) | 0.125 |
   Positive | 11 (33.3) | 0 |  | 28 (100) | 3 (75) |  |
   Negative | 22 (66.7) | 8 (100) |  | 0 | 1 (25) |  |
P53 | (30) | (7) | 1.00 | (26) | (4) | 0.601 |
   Positive | 14 (46.7) | 4 (57.1) |  | 13 (50) | 3 (75) |  |
   Negative | 16 (53.3) | 3 (42.9) |  | 13 (50) | 1 (25) |  |