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Figure 4 | Breast Cancer Research

Figure 4

From: Immortalized, premalignant epithelial cell populations contain long-lived, label-retaining cells that asymmetrically divide and retain their template DNA

Figure 4

Asymmetric cell division occurred in immortalized, premalignant cell populations. Fat pads from mice implanted with immortalized, premalignant cells were labeled with 5-BrdU and 3H-TdR. Double-labeled cells that undergo asymmetric division and pass a 3H-TdR label on to their daughter cell (red arrow) in (a) nulliparous and (b) pregnant mice were identified by using light microscopy. Scale bars equal 5 μm.

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