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Figure 3 | Breast Cancer Research

Figure 3

From: Immortalized, premalignant epithelial cell populations contain long-lived, label-retaining cells that asymmetrically divide and retain their template DNA

Figure 3

Diagram of symmetric and asymmetric division. Brown background indicates a cell with template DNA; black dots indicate a cell that is cycling. (a) During symmetric division, a cycling (black dots) parent cell with template DNA (brown background) divides equally, yielding two proliferating (black dots) identical daughter cells that each have one template DNA strand (brown background) and one newly synthesized DNA strand. (b) In asymmetric division, a cycling (black dots) parent (stem) cell with template DNA (brown background) undergoes unequal division, retaining its template DNA (brown background), but yielding one proliferating (black dots) daughter cell containing DNA that was newly synthesized from the parent's template strand.

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