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Table 1 Prognostic performance of individual HRneg/Tneg gene candidates in the HRneg training cohort (n = 199)

From: A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer

Affymetrix ID

Gene symbol

Gene title

Univariate Cox analysis

Multivariate Cox analysis

   

Coefficient

Pvalue

Coefficient

Pvalue

204338_s_at

RGS4

Regulator of G-protein signaling 4

0.24

2.64 × 10-3

0.16

0.12

205242_at

CXCL13

Chemokine (C-X-C motif) ligand 13 (B-cell chemoattractant)

-0.19

1.90 × 10-5

-0.16

6.0 × 10-4

205523_at

HAPLN1

Hyaluronan and proteoglycan link protein 1

0.17

1.04 × 10-3

0.18

1.4 × 10-3

206821_x_at

HRBL

HIV-1 Rev binding protein-like

-0.48

6.96 × 10-4

-0.22

0.18

206904_at

MATN1

Matrilin 1, cartilage matrix protein

-0.50

8.97 × 10-5

-0.11

0.45

207341_at

PRTN3

Proteinase 3 (serine proteinase, neutrophil, Wegener granulomatosis autoantigen)

-0.41

2.64 × 10-4

-0.12

0.37

207666_x_at

SSX3

Synovial sarcoma, X breakpoint 3

-0.33

2.17 × 10-3

-0.42

5.8 × 10-4

208902_s_at

RPS28///ANKRD47

Ribosomal protein S28///Ankyrin repeat domain 47

-0.59

1.08 × 10-3

-0.56

4.7 × 10-3

212035_s_at

EXOC7

Exocyst complex component 7

-0.58

2.47 × 10-4

-0.42

2.4 × 10-2

216929_x_at

ABO

ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)

-0.44

3.26 × 10-4

-0.23

9.2 × 10-2

217628_at

CLIC5

Chloride intracellular channel 5///similar to chloride intracellular channel 5

-0.48

1.89 × 10-4

-0.24

0.13

218430_s_at

RFXDC2

Regulatory factor X domain containing 2

-0.47

2.57 × 10-4

-0.40

4.6 × 10-3

219605_at

ZNF3

Zinc finger protein 3

-0.34

4.85 × 10-3

-0.30

4.5 × 10-2

220433_at

PRRG3

Proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)

-0.47

4.95 × 10-4

-0.27

6.2 × 10-2

  1. HRneg, hormone receptor-negative; Tneg, triple-negative.