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Figure 2 | Breast Cancer Research

Figure 2

From: 17-allyamino-17-demethoxygeldanamycin treatment results in a magnetic resonance spectroscopy-detectable elevation in choline-containing metabolites associated with increased expression of choline transporter SLC44A1 and phospholipase A2

Figure 2

Effect of 17-AAG on cell proliferation and Hsp90 client protein levels. (a) Western blot analysis showing depletion of Hsp90 client proteins total-Akt and c-Raf following 17-AAG treatment of MCF-7 cells for 48 hours. Actin was used as a loading control. (b) Results of WST-1 assay showing 17-AAG effects on MCF-7 cell proliferation over a 48-hour treatment period. 17-AAG, 17-allyamino-17-demethoxygeldanamycin; Hsp90, heat shock protein 90.

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Breast Cancer Research

ISSN: 1465-542X

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