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Figure 1 | Breast Cancer Research

Figure 1

From: 17-allyamino-17-demethoxygeldanamycin treatment results in a magnetic resonance spectroscopy-detectable elevation in choline-containing metabolites associated with increased expression of choline transporter SLC44A1 and phospholipase A2

Figure 1

Schematic of choline phospholipid metabolism. Schematic drawing of choline phospholipid metabolism and its regulatory enzymes illustrates the metabolic reactions associated with modulation of choline-containing metabolites. CCT, CTP:phosphocholine cytidylyltransferase; CDP-choline, cytidine diphosphate-choline; ChoK, choline kinase; CPT, diacylglycerol cholinephosphotransferase; GDPD, glycerophosphocholine phosphodiesterase; GPC, glycerophosphocholine; LPL, lysophospholipase; PC, phosphocholine; PLA, phospholipase A; PLC, phospholipase C; PLD, phospholipase D; PtdCho, phosphatidylcholine.

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Breast Cancer Research

ISSN: 1465-542X

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