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Table 3 Hazard of invasive breast cancer according to each component cause, adjusting for potential confounders, in postmenopausal women (50-79 years old) enrolled in the Women's Health Initiative Observational Study (1993-2003)

From: Family history of later-onset breast cancer, breast healthy behavior and invasive breast cancer among postmenopausal women: a cohort study

  Component one Component two
  FHLBC Breast healthy behavior
  Crude HR (95% CI) Crude HR (95% CI)
  1.50 (1.33, 1.68) 0.76 (0.60, 0.97)
Potential confounders Adjusted HR (95% CI) Adjusted HR (95% CI)
   Age 1.48 (1.31, 1.66) 0.77 (0.61, 0.99)
   Education N/A 0.75 (0.59, 0.95)
   Caucasian 1.47 (1.30, 1.65) 0.77 (0.61, 0.97)
   Income of less than $35,000/year N/A 0.77 (0.60, 0.98)
   No mammogram in past 2 years 1.48 (1.31, 1.67) 0.74 (0.58, 0.94)
   Breast biopsy ever 1.44 (1.28, 1.63) N/A
   Current hormone therapy use 1.52 (1.35, 1.71) 0.74 (0.58, 0.94)
   Menarche at less than 12 years of age N/A 0.77 (0.61, 0.98)
   Never pregnant N/A N/A
  1. CI, confidence interval; FHLBC, family history of later-onset breast cancer; HR, hazard ratio; N/A, not applicable, because these factors were not associated with the component cause and thus are not potential confounding variables for the interaction contrast.