Figure 4
From: An ELISA-based high throughput protein truncation test for inherited breast cancer
Example of BRCA1 mRNA-based high-throughput solid-phase protein truncation test (HTS-PTT). mRNA extracted from 13 cell-line samples was analyzed by means of the HTS-PTT. % C/N is the C- to N-terminal signal ratio of a given sample normalized against known wild-type controls. The mutant sample is designated by the red bar. BRCA1/BRCA2, breast and ovarian cancer susceptibility gene 1/2.