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Table 2 Median (interquartile range) expression of markers ER, PgR, Ki67, p-Akt and p-Erk1/2 in samples A, B and C as defined in the text*

From: Extreme loss of immunoreactive p-Akt and p-Erk1/2 during routine fixation of primary breast cancer

Marker Sample A Sample B Sample C Pvalue
Ki67 16.4 (9.4-21.7) 17.1 (7.0-25.1) 15.3 (8.0-19.6) 0.19
ER 190.4 (171.2-200.5) 194.7 (167.6-199.4) 188.0 (145.1-195.4) 0.06
PgR 158.9 (58.3-193.3) 161.0 (97.2-189.0) 153.3 (42.2-193.2) 0.89
HER2 3+: 1; 2+: 2; 1+: 14; 0: 4 3+: 1; 2+: 2; 1+: 13; 0: 4 3+: 1; 2+: 2; 1+: 3; 0: 15 0.0012
p-Akt 111.4 (60.8-178.6) 101.1 (75.4-146.0) 26.8 (5.0-75.4) <0.0001
p-Erk1/2 212.2 (123.6-243.6) 193.1 (113.5-238.0) 69.3 (0.4-113.5) <0.0001
  1. *Numerical values for samples A, B and C refer to H scores (for ER, PgR, p-Erk1/2 and p-Akt) and percentage positive scores (for Ki67). For HER2, the number of cases in each staining category is shown. P values refer to comparison between mean A, B and C samples. ER, oestrogen receptor: PgR, progesterone receptor; HER2, human epidermal growth factor receptor 2.