Skip to main content

Table 2 Median (interquartile range) expression of markers ER, PgR, Ki67, p-Akt and p-Erk1/2 in samples A, B and C as defined in the text*

From: Extreme loss of immunoreactive p-Akt and p-Erk1/2 during routine fixation of primary breast cancer

Marker

Sample A

Sample B

Sample C

Pvalue

Ki67

16.4 (9.4-21.7)

17.1 (7.0-25.1)

15.3 (8.0-19.6)

0.19

ER

190.4 (171.2-200.5)

194.7 (167.6-199.4)

188.0 (145.1-195.4)

0.06

PgR

158.9 (58.3-193.3)

161.0 (97.2-189.0)

153.3 (42.2-193.2)

0.89

HER2

3+: 1; 2+: 2; 1+: 14; 0: 4

3+: 1; 2+: 2; 1+: 13; 0: 4

3+: 1; 2+: 2; 1+: 3; 0: 15

0.0012

p-Akt

111.4 (60.8-178.6)

101.1 (75.4-146.0)

26.8 (5.0-75.4)

<0.0001

p-Erk1/2

212.2 (123.6-243.6)

193.1 (113.5-238.0)

69.3 (0.4-113.5)

<0.0001

  1. *Numerical values for samples A, B and C refer to H scores (for ER, PgR, p-Erk1/2 and p-Akt) and percentage positive scores (for Ki67). For HER2, the number of cases in each staining category is shown. P values refer to comparison between mean A, B and C samples. ER, oestrogen receptor: PgR, progesterone receptor; HER2, human epidermal growth factor receptor 2.