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Table 3 Comparison of various combinations of three diagnostic methods for preoperative prediction of histologically confirmed invasive cancer (n = 185) or benign disease (n = 254)

From: Comparison of written reports of mammography, sonography and magnetic resonance mammography for preoperative evaluation of breast lesions, with special emphasis on magnetic resonance mammography

Diagnostic methods

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Accuracy (%)

Mammography + MR mammography

98.9*

90.5

88.4

99.1*

94.1

Sonography + MR mammography

98.9*

93.3

91.5

99.2*

95.7

Mammography + sonography

94.6

92.1

89.7

95.9

93.2

All three methods combined

99.4†

95.3

93.9

99.6†

97.0†‡

  1. * P < 0.05, versus mammography and sonography; † P < 0.005, versus mammography and sonography; ‡ P < 0.05, versus MR mammography and mammography. NPV, negative predictive value; PPV, positive predictive value.