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Table 1 Analysis of Msx2 expression at the mRNA level within the van de Vijver dataseta

From: Homeobox transcription factor muscle segment homeobox 2 (Msx2) correlates with good prognosis in breast cancer patients and induces apoptosis in vitro

Variable Van de Vijver data set (n= 295)
  Low Msx2
(n= 74)
High Msx2
(n= 221)
P value
Age    0.592
   ≤50 65 (87.8) 199 (90)  
   > 50 9 (12.2) 22 (10)  
Tumour size    0.297
   ≤2 cm 35 (47.3) 120 (54.3)  
   > 2 cm 39 (52.7) 101 (45.7)  
Nodal status    0.056
   Negative 45 (60.8) 106 (48)  
   Positive 29 (39.2) 115 (52)  
Tumour grade    0.003
   Low 12 (16.2) 63 (28.5)  
   Intermediate 20 (27) 81 (36.7)  
   High 42 (56.8) 77 (34.8)  
ER status    <0.001
   Negative 39 (52.7) 30 (13.6)  
   Positive 35 (47.3) 191 (86.4)  
Tumour subtype    <0.001*
   Normal 7 (9.5) 24 (10.9)  
   Luminal A 20 (27) 68 (30.8)  
   Luminal B 11 (14.9) 70 (31.7)  
   Basal 30 (40.5) 16 (7.2)  
   Her2 6 (8.1) 43 (19.5)  
70-gene signature    0.003
   Poor 56 (75.7) 124 (56.1)  
   Good 18 (24.3) 97 (43.9)  
  1. aER, estrogen receptor; *Fisher's exact test;, otherwise, χ2 test.