Table 1 Analysis of Msx2 expression at the mRNA level within the van de Vijver dataseta
Variable | Van de Vijver data set (n= 295) | ||
|---|---|---|---|
Low Msx2 (n= 74) | High Msx2 (n= 221) | P value | |
Age | 0.592 | ||
≤50 | 65 (87.8) | 199 (90) | |
> 50 | 9 (12.2) | 22 (10) | |
Tumour size | 0.297 | ||
≤2 cm | 35 (47.3) | 120 (54.3) | |
> 2 cm | 39 (52.7) | 101 (45.7) | |
Nodal status | 0.056 | ||
Negative | 45 (60.8) | 106 (48) | |
Positive | 29 (39.2) | 115 (52) | |
Tumour grade | 0.003 | ||
Low | 12 (16.2) | 63 (28.5) | |
Intermediate | 20 (27) | 81 (36.7) | |
High | 42 (56.8) | 77 (34.8) | |
ER status | <0.001 | ||
Negative | 39 (52.7) | 30 (13.6) | |
Positive | 35 (47.3) | 191 (86.4) | |
Tumour subtype | <0.001* | ||
Normal | 7 (9.5) | 24 (10.9) | |
Luminal A | 20 (27) | 68 (30.8) | |
Luminal B | 11 (14.9) | 70 (31.7) | |
Basal | 30 (40.5) | 16 (7.2) | |
Her2 | 6 (8.1) | 43 (19.5) | |
70-gene signature | 0.003 | ||
Poor | 56 (75.7) | 124 (56.1) | |
Good | 18 (24.3) | 97 (43.9) | |