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Table 3 Sensitivity analysis for the cohort born in 1945

From: Breast cancer incidence and overdiagnosis in Catalonia (Spain)

Screening pattern Parameter change Overdiagnosis (%)
Annual (z = 40) - 26.4
Annual (z = 40) β = 0.9 25.0
Annual (z = 40) α = 1 51.1
Annual (z = 40) α = 5 18.3
Biennial (z = 40) - 33.9
Mamo dissem 1994 for 40 to 49 years - 33.8
Mamo dissem 2006 for 60 to 69 years - 29.3
  1. To test the sensitivity of the model we changed some of the parameters and estimated overdiagnosis for woman born in 1945. The modified parameters were mammography sensitivity (β) and mean sojourn time in pre-clinical state (α). In the first five scenarios, 100% of the population started receiving mammography at age 40 (z = 40). The last two scenarios take into account the actual dissemination of mammography, and use as proportions of repeat mammography behavior the most extreme vañues found in the different health surveys (see Methods).