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Figure 4 | Breast Cancer Research

Figure 4

From: Association of invasion-promoting tenascin-C additional domains with breast cancers in young women

Figure 4

In situ localisation of tenascin-C additional domain 1 to tumour cells and normal myoepithelial cells. (a) An example of infiltrating ductal carcinoma positive for tenascin-C additional domain 1 (TNC-AD1) by RT-PCR: (i) H & E; (ii) in situ hybridisation using antisense probe to the TNC-AD1 domain, demonstrating signal in tumour cells; (iii) ISH using TNC-AD1 sense probe as a negative control. (b) A normal breast duct with adjacent tumour cells within a lymphovascular space: (i) H & E; (ii) ISH with antisense probe to TNC-AD1 showing signal in scattered myoepithelial cells of normal ducts as well as localised to tumour cells; (iii) ISH with TNC-AD1 sense probe as a negative control.

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