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Table 1 Quantitative analysis of apoptotic and necrotic cells after tamoxifen and nelfinavir treatment

From: Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells

Cell line LL (%) UL (%) UR (%) LR (%)
T47D     
   Control 98.78 0.44 0.77 0.03
   TAM 6 μg/ml 92.71 4.42 2.71 0.17
   NFV 6 μg/ml 95.50 2.17 2.31 0.03
   TAM/NFV 11.18 43.05 44.44 1.34
MCF7     
   Control 88.04 3.10 7.52 1.33
   TAM 6 μg/ml 83.05 7.16 6.89 2.90
   NFV 6 μg/ml 92.80 2.46 3.80 0.95
   TAM/NFV 63.68 14.63 19.48 2.21
  1. The relative cell distributions among the quadrants shown in Figure 2 were analysed using the BectonDickinson CellQuest software. LL, lower left (unstained; viable); UL, upper left (annexin-positive; apoptotic); UR, upper right (annexin-positive and propidium iodide-positive; apoptotic/necrotic); LR, lower right (propidium iodide permeable; necrotic); TAM, tamoxifen; NFV, nelfinavir.