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Table 2 Regions amplified with a frequency of >1% in the 359 tumors

From: Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

Amplified region Percentage of amplified samples Significantly correlated genes
1q21.1 1.1 BCL9, ACP6
1q32.1-q32.2 1.9 BTG2, ATP2B4, SOX13, GOLT1A, PLEKHA6, PPP1R15B, MDM4, RBBP5, RIPK5, ELK4, RAB7L1, SRGAP2, IKBKE, LGTN, DYRK3, MAPKAPK2,
6q21 1.4 BVES, AIM1
6q22.33-q23.1 1.1 PTPRK, L3MBTL3
8p12-p11.23 5.8 ZNF703, SPFH2, PROSC, RAB11FIP1, ADRB3, BAG4, PPAPDC1B, WHSC1L1, FGFR1
8q22.2-q22.3 3.1 VPS13B, RNF19, ANKRD6, GRHL2, EDD1, AZIN1, ATP6V1C1, FZD6, SLC25A32
8q23.3-q24.11 6.1 TRPS1, THRAP6, EXT1
8q24.13-q24.22 6.7 ZHX1, ATAD2, C8orf32, FBXO32, TMEM65, TRMT12, RNF139, TATDN1, KIAA0196, C8orf36, TRIB1, FAM84B, MYC, DDEF1
10p15.3 1.1 PFKP, PITRM1
10p14 1.4  
10q22.3 1.4 POLR3A, RAI17, PPIF
11q13.3-q13.4 6.4 CCND1, FADD, PPFI1A, CTTN
11q13.5-q14.1 3.6 PHCA, CAPN5, MYO7A, PAK1, HBXAP, ALG8, LOC283219, GAB2
12p13.33 1.7 JARID1A, WNK1, RAB6IP2, FBXL14, WNT5B, ADIPOR2, DCP1B
12p13.31 1.4 CD9, TNFRSF1A, LTBR, TAPBPL, MRPL51, NOL1, CHD4, ING4, ZNF384, COPS7A, MLF2, PTMS, USP5, SPSB2, ENO2, ATN1, PTPN6, PHB2, C1 S, C1RL, CLSTN3, PEX5
12q15 1.9 MDM1, NUP107, SLC35E3, MDM2, CPSF6, YEATS4, FRS2, CCT2, CNOT2
17q11.2 3.6 UNC119, PIGS, ALDOC, SPAG5, KIAA0100, SDF2, SUPT6 H, RAB34, NEK8, ERAL1, FLOT2, PHF12, LOC116236, GIT1, ANKRD13B, CORO6, SSH2
17q12.1-q21.1 13.6 FBXL20, PPARBP, STARD3, PERLD1, HER2, C17orf37, GRB7, GSDML, ORMDL3, PSMD3, THRAP4
17q21.33 4.2 LOC81558, ITGA3, PDK2, PPP1R9B, XYLT2, MRPL27, FLJ20920, RSAD1, EPN3, ABCC3, ANKRD40, TOB1
17q23.2 3.1 TRIM25, AKAP1, MSI2
17q23.2 3.1 TMEM49, TUBD1, ABC1, USP32, APPBP2, BCAS3
17q23.3-q24.1 2.5 CYB561, WDR68, MAP3K3, LYK5, DDX42, FTSJ3, PSMC5, SMARCD2, ERN1, POLG2, DDX5, SMURF2
19p13.13-p13.2 1.1 SIPA1L3, PPP1R14A, SPINT2, YIF1B, EIF3S12
19p13.2 1.1 FBL, PSMC4, FLJ36888, PLD3
19q13.42 1.4 SUV42OH2, KLP1, ZNF579, FLJ14768, ZNF524, LOC147808, ZNF580, ZNF581
20q13.31-q13.32 1.1 RAE1, RNPC1, RAB22A, VAPB, STX16, GNAS, TH1L, CTSZ
  1. Genes with significant correlation (P < 0.05) between mRNA expression and DNA copy-number status are indicated for each region.