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Table 1 Patient and tumor characteristics for the 359 tumors

From: Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

Number of tumors

359

Number of primary tumors

346

Number of primary BRCA1-mutated tumors

17

Number of primary BRCA2-mutated tumors

31

Number of primary familial non-BRCA1/2 tumors

126

Tumor size

 

   ≤20 mm

145 (45%)

   > 20 mm

175 (55%)

   Mean size mm (SD)

25.8 (15)

Histologic grading

 

   Grade 1

26 (11%)

   Grade 2

100 (43%)

   Grade 3

106 (46%)

Estrogen-receptor status

 

   Positive

227 (66%)

   Negative

119 (34%)

Progesterone-receptor status

 

   Positive

194 (57%)

   Negative

149 (43%)

Lymph-node status

 

   Negative

190 (58%)

   Positive

137 (42%)

Age

 

   Median age, years (range)

49 (27-88)

   < 50 years

182 (51%)

   ≥ 50 years

174 (49%)

Classification according to Hu et al. [4]

 

   Basal-like

79 (22%)

   Normal-like

34 (9%)

   HER2-enriched

34 (9%)

   Luminal A

95 (26%)

   Luminal B

70 (19%)

   Unclassified

47 (13%)

Overall survival

 

   Median overall survival in years (range)

8.1 (0.24-32)

Median overall survival in years for patients still alive (range)

12.8 (1.55-20.2)

  1. Survival is given for the 346 patients from whom primary tumors were available.