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Table 1 Patient and tumor characteristics for the 359 tumors

From: Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

Number of tumors 359
Number of primary tumors 346
Number of primary BRCA1-mutated tumors 17
Number of primary BRCA2-mutated tumors 31
Number of primary familial non-BRCA1/2 tumors 126
Tumor size  
   ≤20 mm 145 (45%)
   > 20 mm 175 (55%)
   Mean size mm (SD) 25.8 (15)
Histologic grading  
   Grade 1 26 (11%)
   Grade 2 100 (43%)
   Grade 3 106 (46%)
Estrogen-receptor status  
   Positive 227 (66%)
   Negative 119 (34%)
Progesterone-receptor status  
   Positive 194 (57%)
   Negative 149 (43%)
Lymph-node status  
   Negative 190 (58%)
   Positive 137 (42%)
Age  
   Median age, years (range) 49 (27-88)
   < 50 years 182 (51%)
   ≥ 50 years 174 (49%)
Classification according to Hu et al. [4]  
   Basal-like 79 (22%)
   Normal-like 34 (9%)
   HER2-enriched 34 (9%)
   Luminal A 95 (26%)
   Luminal B 70 (19%)
   Unclassified 47 (13%)
Overall survival  
   Median overall survival in years (range) 8.1 (0.24-32)
Median overall survival in years for patients still alive (range) 12.8 (1.55-20.2)
  1. Survival is given for the 346 patients from whom primary tumors were available.