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Table 6 Response of women to neoadjuvant chemotherapy according to final nodal status

From: The role of chemotherapeutic drugs in the evaluation of breast tumour response to chemotherapy using serial FDG-PET

 

All women

TAX → FEC

FEC → TAX

P valuea

≥ 75% reduction in SUVmax

28/57 (49.1)

17/28 (60.7)

11/28 (39.3)

0.63

Node-negative

18/28 (64.2)

8/18 (44.4)

10/18 (55.5)

0.9

Node-positive

10/28 (35.7)

9/10 (90.0)

1/10 (10.0)

0.001

  1. Response of women to neoadjuvant chemotherapy according to final nodal status (positive or negative nodes at surgery). Women were stratified according to drug sequence and > 75% reduction in maximal standard uptake volume (SUVmax) of [18F]flourodeoxyglucose after four cycles. Data presented as n/N (%) (total number = 57). TAX, docetaxel (Taxotere®); FEC, combined flourouracil-epirubicin-cyclophosphamide anthracycline-based chemotherapy. aChi-square test (comparison of the two treatment arms).