Skip to main content
Figure 6 | Breast Cancer Research

Figure 6

From: Progesterone reverses the mesenchymal phenotypes of basal phenotype breast cancer cells via a membrane progesterone receptor mediated pathway

Figure 6

Co-localization of mPRα and EGFR in caveolar membrane of MB468 cells. Caveolar (Cav) fractions were isolated and immunoblotted for detecting Cav-1, membrane progesterone receptor (mPR) α, and epidermal growth factor receptor (EGFR) after the MB468 cells were treated (a) without and (b) with progesterone (P4) at 30 ng/ml for 24 hours. The Figures 6a and b show that Cav-1, mPRα, and EGFR are co-localized in the caveolar fraction #3 component regardless of P4 treatments. The results are representative for two separate experiments. PC, mPRα positive cells (HEK293).

Back to article page