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Figure 5 | Breast Cancer Research

Figure 5

From: Progesterone reverses the mesenchymal phenotypes of basal phenotype breast cancer cells via a membrane progesterone receptor mediated pathway

Figure 5

The molecular pathways involved in the P4-repressed EMT of MB468 cells. Growth-arrested MB468 cells were treated with (a) AG1478 (1 μM) or PP1 (10 μM) and wortmannin (0.1 μM) or (b) PD98059 (50 μM) for one hour, followed by progesterone (P4) treatment at 30 ng/ml for 24 hours. Western blot analyses were performed with diverse anti-snail and/or epithelial-mesenchymal transition (EMT) relevant antibodies as indicated. The data are representative for three individual experiments.

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Breast Cancer Research

ISSN: 1465-542X

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