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Table 4 General characteristic of triple-negative breast cancers

From: Triple-negative breast cancer

Often present as interval cancer
Weak association between tumor size and lymph node involvement
High risk of early recurrence
Peak recurrence rate is seen between the first and third years after diagnosis
Metastases are rarely preceded by local recurrence
Local recurrence is not predictive of metastatic disease
More prevalent in young women
Stronger association with obesity
Higher prevalence of brain metastases
Most deaths occur in the first 5 years
Rapid progression from the onset of metastasis to death
Highly chemosensitive
Risk factor in tumors with negative axillary nodes
Specific target molecules have only been determined recently