Figure 3From: Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 AktsTherapeutic drugs that target various components of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. EGFR, epidermal growth factor receptor; HER2, human epidermal growth factor receptor 2; mTOR, mammalian target of rapamycin; VEGFR, vascular endothelial growth factor receptor.Back to article page