Skip to main content

Advertisement

Table 5 Expression of HSP90, PI3K-p110α, and PTEN loss according to intrinsic subtypes

From: Potential prognostic value of heat-shock protein 90 in the presence of phosphatidylinositol-3-kinase overexpression or loss of PTEN, in invasive breast cancers

  Luminal A (n = 131) Luminal B (n = 18) Triple negative (n = 37) HER2+/ER- (n = 26) Pvalue
  n (%) n (%) n (%) n (%)  
HSP90 86 (66) 13 (72) 18 (49) 17 (65) 0.208
PI3K-p110α 79 (62) 13 (72) 25 (68) 21 (81) 0.296
PTEN loss 29 (22) 6 (33) 17 (46) 5 (19) 0.023
  1. HSP90 = heat-shock protein 90; PI3K = phosphatidylinositol-3-kinase; PTEN = phosphatase and tensin homologue deleted on chromosome 10.