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Table 5 Expression of HSP90, PI3K-p110α, and PTEN loss according to intrinsic subtypes

From: Potential prognostic value of heat-shock protein 90 in the presence of phosphatidylinositol-3-kinase overexpression or loss of PTEN, in invasive breast cancers

 

Luminal A

(n = 131)

Luminal B

(n = 18)

Triple negative

(n = 37)

HER2+/ER-

(n = 26)

Pvalue

 

n

(%)

n

(%)

n

(%)

n

(%)

 

HSP90

86

(66)

13

(72)

18

(49)

17

(65)

0.208

PI3K-p110α

79

(62)

13

(72)

25

(68)

21

(81)

0.296

PTEN loss

29

(22)

6

(33)

17

(46)

5

(19)

0.023

  1. HSP90 = heat-shock protein 90; PI3K = phosphatidylinositol-3-kinase; PTEN = phosphatase and tensin homologue deleted on chromosome 10.
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Breast Cancer Research

ISSN: 1465-542X

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