From: Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer
Pathway
Number of SNPs
P heterogeneity
P trenda
Whole pathway
239
0.840
0.507
Androgen synthesis
11
0.761
0.763
Androgen to estrogen conversion
120
0.587
0.715
Estrogen removal
134
0.834
0.872