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Table 4 Results of multivariate analysis of independent prognostic factors in patients with breast cancer using Cox regression

From: The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer

 

Disease-Free survival

Overall survival

Factor

Hazard ratio (95% CI)

P value

Hazard ratio (95% CI)

P value

HJURP expression+

2.05 (1.18 to 3.58)

0.011

1.83 (1.11 to 3.01)

0.018

Lymph node (positive)

3.76 (1.16 to 12.25)

0.028

2.72 (1.08 to 6.88)

0.035

High Stage

2.23 (1.08 to 4.59)

0.030

1.85 (0.94 to 3.63)

0.075

Tumor size

1.32 (0.97 to 1.79)

0.079

1.34 (1.02 to 1.77)

0.038

Age (year)

1.01 (0.99 to 1.05)

0.33

1.03 (1.004 to 1.053)

0.022

High SBR Grade

0.76 (0.33 to 1.75)

0.52

1.00 (0.50 to 2.00)

0.99

ER (positive)

0.63 (0.21 to 1.94)

0.42

0.86 (0.33 to 2.25)

0.75

PR (positive)

0.90 (0.33 to 2.50)

0.84

0.95 (0.40 to 2.26)

0.91

  1. + HJURP expression is measured as log2 (probe intensities) by Affymetrix microarray