Figure 5
Validation of the association between HJURP mRNA and disease-free survival in another two independent cohorts. Kaplan-Meier survival curves for breast cancer patients according to tumor expression of HJURP are shown. The patients from each cohort were divided into a group with high (top one-third), moderate (middle one-third) and low (bottom one-third) level of HJURP expression. HJURP expression is measured log2 (probe intensities) as in the microarray. The significant association between HJURP mRNA and disease-free survival was further validated in two independent cohorts of patients with breast cancer. Parts (a) and (b) show the Kaplan-Meier survival curves for disease-free survival in Dataset 4 (GSE2034) and Dataset 5 (GSE4922). The P-values shown were obtained from a long-rank test.