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Figure 4 | Breast Cancer Research

Figure 4

From: The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer

Figure 4

Validation of the association between HUJRP mRNA and prognosis in three independent cohorts. Kaplan-Meier survival curves for breast cancer patients according to tumor expression of HJURP are shown. The patients from each cohort were divided into a group with high (top one-third), moderate (middle one-third) and low (bottom one-third) level of HJURP expression. HJURP expression is measured log2 (probe intensities) as in the microarray. The significant association between HJURP mRNA and disease-free and overall survival was validated in three independent cohorts of patients with breast cancer. Parts (a), (b) and (c) show the Kaplan-Meier survival curves for disease-free and overall survival in Dataset 1 (GSE1456), Dataset 2 (GSE7390) and Dataset 3 (NKI) respectively. The P-values shown were obtained from a long-rank test.

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