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Table 3 Duration and intensity of NSAID¤ use among women with ≥ 10 years of prescription history

From: Prescriptions for selective cyclooxygenase-2 inhibitors, non-selective non-steroidal anti-inflammatory drugs, and risk of breast cancer in a population-based case-control study

Characteristics Cases* Controls* Odds Ratio 95% Confidence Interval
  N % N %   
Never/rare 1,188 50 12,714 53 1.00  
Shorter-term <10 years:       
   Low Intensity† 317 13 2,997 13 1.09 0.96 to 1.25
   Medium Intensity‡ 210 9 2,078 9 1.03 0.88 to 1.20
   High Intensity+ 332 14 2,961 12 1.16 1.01 to 1.33
Long-term 10 to </= 15 years:       
   Low Intensity† 151 6 1,301 5 1.18 0.98 to 1.42
   Medium Intensity‡ 81 3 773 3 1.06 0.83 to 1.35
   High Intensity+ 88 4 971 4 0.90 0.71 to 1.13
Long-term >15 years:       
   Low Intensity† 6 0.3 76 0.3 0.80 0.35 to 1.85
   Medium Intensity‡ 16 0.7 74 0.3 2.30 1.30 to 4.06
   High Intensity+ 10 0.4 96 0.4 1.01 0.52 to 1.97
  1. ¤(sCox-2 inhibitors, aspirin, and non-aspirin non-selective NSAID). * Matched on county of residence and birth year. ^Analyses adjusted for use of hormone replacement therapy, history of rheumatoid arthritis and migraine. † Low intensity was prescription use <25% of duration. ‡ Medium intensity was prescription use >25% but <50% of duration. + High intensity was prescription use >50% of duration.
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