MCF-7 | |||||
---|---|---|---|---|---|
CD24Low/-/CD44Hight | ZsGreen-cODC+ | ||||
Dose | % of CICs (+/- SEM) | Sphere forming capacity | Sphere forming capacity | % of CICs (+/- SEM) | Dose |
0 | 3.01 (+/- 0.61), P value | 9.4 (+/- 0.5), P value | 12.32 (+/- 2.01), P value | 2.17 (+/- 0.47), P value | 0 |
2 | 6.54 (+/- 1.95), P = 0.095 | 13.49 (+/- 1.32), P = 0.01 | 15.25 (+/- 3.2), P = 0.661 | 3.70 (+/- 0.52), P = 0.051 | 3 |
2 × 2 | 8.04 (+/- 1.47), P = 0.036 | 10.76 (+/- 0.96), P = 0.137 | 17.54 (+/- 4.15), P = 0.096 | 3.13 (+/- 0.53), P = 0.252 | 2 × 3 |
4 × 2 | 8.56 (+/- 1.21), P = 0.020 | 11.85 (+/- 1.81), P = 0.198 | 17.93 (+/- 2.33), P = 0.051 | 6.73 (+/- 1.33), P = 0.141 | 3 × 3 |
6 × 2 | 9.10 (+/- 1.04), P = 0.029 | 11.85 (+/- 1.48), P = 0.035 | 24.52 (+/- 4.50), P = 0.048 | 11.26 (+/- 2.06), P = 0.091 | 4 × 3 |
8 × 2 | 4.78 (+/- 0.34) P = 0.229 | 11.85 (+/- 1.27), P = 0.002 | 25.37 (+/- 5.2), P = 0.039 | 12.64 (+/- 1.91), P = 0.044 | 5 × 3 |
T47D | |||||
CD24 Low/- /CD44Hight | ZsGreen-cODC+ | ||||
Dose | % of CICs (+/- SEM) | Sphere forming capacity | Sphere forming capcity | % of CICs (+/- SEM) | Dose |
0 | 0.35 (+/- 0.06), P value | 9.46 (+/- 2.20), P value | 3.35 (+/- 2.01), P value | 2.47 (+/- 0.88), P value | 0 |
2 | 0.34 (+/- 0.03), P = 0.868 | 6.74 (+/- 1.31), P = 0.014 | 3.13 (+/- 2.69), P = 0.231 | 4.31 (+/- 1.13), P = 0.029 | 3 |
2 × 2 | 0.43 (+/- 0.08), P = 0.471 | 13.76 (+/- 4.01), P = 0.146 | 6.48 (+/- 3.14), P = 0.091 | 9.72 (+/- 2.81), P = 0.068 | 2 × 3 |
4 × 2 | 2.04 (+/- 0.12), P = 0.001 | 12.74 (+/- 4.58), P = 0.157 | 9.96 (+/- 2.33), P = 0.049 | 16.09 (+/- 5.57), P = 0.103 | 3 × 3 |
6 × 2 | 0.68 (+/- 0.04), P = 0.007 | 17.99 (+/- 5.17), P = 0.027 | 12 (+/- 2.66), P = 0.033 | 24.06 (+/- 4.15), P = 0.025 | 4 × 3 |
8 × 2 | 0.29 (+/- 0.01), P = 0.449 | 18.92 (+/- 5.83), P = 0.018 | 7.65 (+/- 2.55), P = 0.055 | 21.133 (+/- 1.87), P = 0.015 | 5 × 3 |