Skip to main content

Advertisement

Table 5 Functional enrichment of genes expressed lower in blood of breast cancer patients compared to healthy subjects

From: Gene expression profiling of peripheral blood cells for early detection of breast cancer

Biological process Count % P-Value Genes Fold Enrichment FDR
GO:0044255 Cellular lipid metabolic process 20 7.69% 0.0008 C10orf33, MBTPS1, PMVK, OSBPL7, SULT1A2, PEMT, LASS6, CMAS, SYK, PLAA, SULT1A4, INSIG1, IDI1, FDPS, HEXA, PECI, CYP2J2, ACAA1, SULT1A1, GRN, 2.3 1.6
GO:0008202 Steroid metabolic process 9 3.46% 0.0022 INSIG1, IDI1, MBTPS1, FDPS, PMVK, OSBPL7, SULT1A2, SULT1A1, SULT1A4, 3.8 4.0
GO:0006629 Lipid metabolic process 21 8.08% 0.0027 C10orf33, MBTPS1, ACAT2, PMVK, OSBPL7, SULT1A2, PEMT, LASS6, CMAS, SYK, PLAA, SULT1A4, INSIG1, IDI1, FDPS, HEXA, PECI, CYP2J2, ACAA1, SULT1A1, GRN, 2.1 4.9
GO:0006584 Catecholamine metabolic process 4 1.54% 0.0057 SULT1A2, HDC, SULT1A1, SULT1A4, 10.3 10.1
GO:0018958 Phenol metabolic process 4 1.54% 0.0057 SULT1A2, HDC, SULT1A1, SULT1A4, 10.3 10.1
  1. FDR = false discovery rate