Figure 4

Association between clinicopathological factors and DNA methylation. A: FOXC1, GSTP1, ABCB1 and RASSF1A were significantly differentially methylated between ER-positive and ER-negative tumours. B: FOXC1, ABCB1, PPP2R2B and PTEN were significantly differentially methylated between TP53 wild type and mutated tumours. C: ABCB1 was significantly differentially methylated between Ki67-negative and Ki67-positive tumours and GSTP1 was significantly differentially methylated between PR-positive and PR-negative tumours. All types of lesions were combined for these analyses. All P-values were obtained by using a false discovery rate <5%.