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Table 1 Patient characteristics for model development (Eastern Cancer Registration and Information Centre-ECRIC) and validation (West Midlands Cancer Intelligence Unit-WMCIU) cohorts

From: PREDICT: a new UK prognostic model that predicts survival following surgery for invasive breast cancer

  ECRIC   WMCIU  
Total Number of Subjects 5,694   5,468  
Total time at risk (years) 31,904   25,917  
Median follow-up (years)* 5.65 (0.04 to 8.00) 4.85 (0.07 to 8.00)
Number of breast cancer deaths 737   668  
Number of other deaths 338   287  
Annual breast cancer mortality rate 0.023 (0.021 to 0.025) 0.026 (0.024 to 0.028)
Five-year breast cancer survival rate 0.89 (0.88 to 0.90) 0.88 (0.87 to 0.89)
Median age at diagnosis, years 58 (23 to 95) 58 (22 to 93)
  Number   Number  
Age, years     
   <35 111 2 108 2
   35 to 49 1,172 21 1,195 22
   50 to 64 2,630 46 2,393 44
   65 to 74 1,124 20 1,101 20
   75+ 657 12 671 12
Nodal status     
   0 3,532 62 3,184 58
   1 741 13 746 14
   2 to 4 806 14 792 14
   5 to 9 380 7 451 8
   10+ 235 4 295 5
Tumour size, mm     
   <10 625 11 485 9
   10 to 19 2,310 41 2,136 39
   20 to 29 1,627 29 1,566 29
   30 to 49 845 15 923 17
   50+ 287 5 358 7
Grade     
   I 1,005 18 1,017 19
   II 2,927 51 2,442 45
   III 1,762 31 2,009 37
Oestrogen Receptor (ER) Status     
   ER negative 991 17 1,116 20
   ER positive 4,703 83 4,352 80
Adjuvant therapy     
   Chemotherapy 1,905 33 2,121 39
   Endocrine therapy 4,268 75 2,406 44
   Combined chemoendocrine 1,122 20 579 11
Screen detected     
   Yes 1,621 28 1,256 23
   No 4,073 72 4,212 77
  1. * Follow-up censored at eight years
  2. Range of variable
  3. 95 CI