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Table 6 Association between YY1 nuclear protein expression with HER-2 gene and protein expression levels

From: Investigating AP-2 and YY1 protein expression as a cause of high HER2 gene transcription in breast cancers with discordant HER2 gene amplification

  

YY1

  

Negative

Positive

χ2

P-value

HER-2 Gene Expression

Normal

315 (40.6%)

190 (49.4%)

13.115

0.004

 

Amplified

68 (8.8%)

16 (4.2%)

  
 

Gain

13 (1.7%)

7 (1.8%)

  

HER-2 Protein Expression

0

366 (67.3%)

178 (32.7%)

19.882

<0.001

 

1+

13 (39.4%)

20 (60.6%)

  
 

2+

21 (4.7%)

7 (3.3%)

  
 

3+

51 (11.3%)

10 (4.7%)

  
  1. Significance level P = 0.05.
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Breast Cancer Research

ISSN: 1465-542X

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