Skip to main content

Table 3 Patients' characteristics showing YY1 protein expression

From: Investigating AP-2 and YY1 protein expression as a cause of high HER2 gene transcription in breast cancers with discordant HER2 gene amplification

 

YY1

 

Variable

Positive (%)

Negative (%)

χ2

(P-value)

Patients age

   
 

26 (6.7)

53 (6.9)

1.454

(0.693)

 

110 (28.5)

196 (25.4)

 
 

119 (30.8)

242 (31.3)

 
 

131 (33.9)

282 (36.5)

 

Primary tumour size

   ≤ 1.5 cm

144 (37.6)

241 (31.1)

4.817

(0.028)

   >1.5 cm

239 (62.4)

533 (68.9)

 

Lymph node Stage

   1

234 (61.1)

492 (63.6)

1.982

(0.371)

   2

118 (30.8)

209 (27.0)

 

   3

31 (8.1)

72 (9.3)

 

Grade

   1

85 (22.2)

113 (14.6)

46.984 (<0.001)

   2

162 (42.3)

220 (28.5)

 

   3

136 (35.5)

440 (56.9)

 

NPI

   Poor

49 (12.8)

193 (24.9)

17.284 (<0.001)

   Moderate

195 (50.9)

444 (57.4)

 

   Good

139 (36.3)

137 (17.7)

 

Development of Distant Metastasis

   No

274 (71.5)

521 (68.2)

1.343

(0.246)

   Positive

109 (28.5)

243 (31.8)

 

Development of Recurrence

   No

226 (59.2)

435 (57.4)

0.328

(0.567)

   Positive

156 (40.8)

323 (42.6)

 

Vascular invasion

   No

232 (60.7)

417 (54.4)

4.45

(0.108)

   Probable

37 (9.7)

94 (12.3)

 

   Definite

113 (29.6)

256 (33.4)

 

Tumour type

   Ductal/NST

195 (51.2)

474 (62.3)

29.509

(<0.001)

   Lobular

53 (13.9)

59 (7.8)

 

   Tubular and Tubular mixed

99 (26.0)

140 (18.4)

 

   Medullary

5 (1.3)

29 (3.8)

 

   Other special types*

8 (2.1)

11 (1.4)

 

   Mixed**

19 (5)

45 (5.9)

 

Menopausal status

   Premenopausal

160 (41.5)

284 (36.7)

2.417 (0.12)

   Postmenopausal

226 (58.5)

489 (63.3)

 
  1. *Includes Mucoid, invasive cribriform and invasive papillary carcinoma. **Includes ductal/No special type (NST) mixed with lobular or special types. NPI = Nottingham Prognostic Index.