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Table 3 Correlation of the presence/absence of Amp13q34 with the protein expression levels of CUL4A and TFDP1

From: Comprehensive characterization of the DNA amplification at 13q34 in human breast cancer reveals TFDP1 and CUL4A as likely candidate target genes

 

CUL4A expression

TFDP1 expression

 

CUL4A

CUL4A

TFDP1

TFDP1

13q34

-ve

+ve

-ve

mid

+ve

-ve

+ve

-ve

+ve1

+ve2

   No amp

155 (65.7)

81 (34.3)

4 (1.7)

151 (64.0)

81 (34.3)

115 (48.1)

124 (51.9)

115 (48.1)

76 (31.8)

48 (20.1)

   Amp

3 (25.0)

9 (75.0)

0 (0)

3 (25.0)

9 (75.0)

1 (7.7)

12 (92.3)

1 (7.7)

2 (15.4)

10 (76.9)

P-values

P = 0.010

P = 0.017*

P = 0.004*

P = < 0.001*

  1. Each cell shows the number of samples and the percentage in the series between brackets.
  2. CUL4A expression levels: a) -ve (negative) (null, low and medium staining) and +ve (positive) (strong staining); b) negative (null staining), mid (low and medium staining) and positive (strong staining).
  3. TFDP1 expression levels: a) negative (< 25%) and positive (> 25%); b) negative (< 25% stained cells), +ve1 (positive) (between 25-60% stained cells), +ve2 (positive) (> 60% stained cells).
  4. *P values from the Chi square of Pearson.
  5. Amp = amplification.
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Breast Cancer Research

ISSN: 1465-542X

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