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Table 1 Patient characteristics

From: Hypoxia-inducible factor-1α and vascular endothelial growth factor expression in circulating tumor cells of breast cancer patients

Age  
Median (range) 57 (30 to 76)
  n (%)
Menopausal status  
Premenopausal 4 (12)
Postmenopausal 30 (88)
Primary breast cancer at presentation 23 (68)
Tumor size (cm)  
1-1.9/2-4.9/≥5/UN 3 (13)/14 (61)/2 (9)/4 (17)
Lymph nodes  
0/1-3/≥4/UN 7 (30)/6 (26)/8 (35)/2 (9)
Grade  
II/III/UN 8 (35)/11 (48)/4 (17)
Disease sites*  
1 5 (15)
2 15 (44)
3 5 (15)
≥4 8 (23)
Unknown 1 (3)
Predominantly visceral disease  
Yes 11 (32)
No 22 (64)
Unknown 1 (3)
Line of treatment **  
0 18 (53)
1 7 (21)
≥2 9 (26)
ER/PR status  
Positive 16 (47)
Negative 13 (38)
Unknown 5 (15)
HER2 status  
Positive*** 7 (20)
Negative 23 (68)
Unknown 4 (12)
  1. UN = unknown,
  2. * Numbers correspond to the number of organs involved
  3. ** Numbers correspond to the number of prior therapies administered for metastatic disease
  4. *** IHC:3+ or FISH positive