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Table 1 Patient characteristics

From: Hypoxia-inducible factor-1α and vascular endothelial growth factor expression in circulating tumor cells of breast cancer patients

Age

 

Median (range)

57 (30 to 76)

 

n (%)

Menopausal status

 

Premenopausal

4 (12)

Postmenopausal

30 (88)

Primary breast cancer at presentation

23 (68)

Tumor size (cm)

 

1-1.9/2-4.9/≥5/UN

3 (13)/14 (61)/2 (9)/4 (17)

Lymph nodes

 

0/1-3/≥4/UN

7 (30)/6 (26)/8 (35)/2 (9)

Grade

 

II/III/UN

8 (35)/11 (48)/4 (17)

Disease sites*

 

1

5 (15)

2

15 (44)

3

5 (15)

≥4

8 (23)

Unknown

1 (3)

Predominantly visceral disease

 

Yes

11 (32)

No

22 (64)

Unknown

1 (3)

Line of treatment **

 

0

18 (53)

1

7 (21)

≥2

9 (26)

ER/PR status

 

Positive

16 (47)

Negative

13 (38)

Unknown

5 (15)

HER2 status

 

Positive***

7 (20)

Negative

23 (68)

Unknown

4 (12)

  1. UN = unknown,
  2. * Numbers correspond to the number of organs involved
  3. ** Numbers correspond to the number of prior therapies administered for metastatic disease
  4. *** IHC:3+ or FISH positive