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Figure 5 | Breast Cancer Research

Figure 5

From: Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2overexpression in breast cancer cell lines

Figure 5

Ku70/80 proteins control ERBB2 promoter activity in BT-474 cell line. Relative luciferase activity in cells transfected with the reporter vectors indicated above the figure, 72 hours after transfection of the siRNAs shown under each bar. The fold induction is the ratio between the luciferase activities in the cells transfected with the siRNA of interest and the activity measured in cells transfected with siRNA Neg. Luciferase activity was normalized to total protein content.

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