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Table 2 Relationship between measures of breast density and six binary variables

From: Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: the UK MARIBS study

  No. 'Yes' No. 'No' coefficient (95% CI) P-value
MRI % dense volume (log)
Ever smoker 229 304 -0.01 (-0.12, 0.10) 0.82
Post-menopausal 108 418 -0.32 (-0.45, -0.19) < 0.001
Ever pregnant 466 64 -0.22 (-0.39, -0.06) 0.008
Ever tamoxifen use 28 506 -0.44 (-0.67, -0.20) < 0.001
Previous OC use 426 106 -0.16 (-0.29, -0.02) 0.023
Ever HRT use 17 97 0.01 (-0.32, 0.33) 0.98
Cumulus %dense area
Ever smoker 206 270 0.21 (-3.43, 3.86) 0.91
Post-menopausal 101 372 -8.95 (-13.3, -4.60) < 0.001
Ever pregnant 424 49 -7.10 (-13.0, -1.18) 0.019
Ever tamoxifen use 30 447 -10.4 (-17.8, -3.07) 0.006
Previous OC use 379 96 0.35 (-4.15, 4.86) 0.88
Ever HRT use 12 73 1.11 (-11.2, 13.4) 0.86
Visually Assessed % dense area
Ever smoker 202 268 -1.25 (-5.05, 2.56) 0.52
Post-menopausal 101 366 -10.3 (-14.8, -5.75) < 0.001
Ever pregnant 418 49 -8.16 (-14.3, -2.03) 0.009
Ever tamoxifen use 29 442 -13.0 (-20.8, -5.28) 0.001
Previous OC use 374 95 -0.39 (-5.08, 4.31) 0.87
Ever HRT use 11 71 5.34 (-7.16, 17.8) 0.41
MRI dense volume (×10 3 , log)
Ever smoker 226 303 0.05 (-0.07, 0.16) 0.43
Post-menopausal 107 415 -0.05 (-0.19, 0.09) 0.50
Ever pregnant 463 63 -0.17 (-0.34, 0.00) 0.05
Ever tamoxifen use 28 502 -0.07 (-0.32, 0.18) 0.60
Previous OC use 423 106 -0.08 (-0.22, 0.06) 0.24
Ever HRT use 17 97 0.12 (-0.24, 0.47) 0.52
Cumulus dense area (×10 3 )
Ever smoker 206 270 41.9 (-156, 240) 0.68
Post-menopausal 101 372 -251 (-491, -10.6) 0.041
Ever pregnant 424 49 -273 (-596, 49.7) 0.098
Ever tamoxifen use 30 447 -273 (-677, 131) 0.19
Previous OC use 379 96 56.1 (-189, 301) 0.65
Ever HRT use 12 73 180 (-419, 778) 0.56