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Figure 4 | Breast Cancer Research

Figure 4

From: Hes-6, an inhibitor of Hes-1, is regulated by 17β-estradiol and promotes breast cancer cell proliferation

Figure 4

Hes-6 is expressed in response to ERα stimulation in MCF-7 cells. (a) Relative Hes-6 mRNA levels in synchronized, non-E2-treated MCF-7 cells (bar 1), non-E2-treated MCF-7 cells after 24 hours (bar 2), and E2-treated MCF-7 cells after 24 hours (bar 3). (b) Relative hASH-1 mRNA levels in synchronized, non-E2-treated MCF-7 cells (bar 1), non-E2-treated MCF-7 cells after 24 hours (bar 2), and E2-treated MCF-7 cells after 24 hours (bar 3). All data are presented as mean values ± SD of three samples/bar. (c) Hes-6 protein in synchronized MCF-7 cells without E2 (column 1), treated with E2 (column 2), and with both E2 and tamoxifen (column 3) for 24 hours.

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