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Figure 6 | Breast Cancer Research

Figure 6

From: PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro

Figure 6

PD 0332991 and tamoxifen in a tamoxifen-insensitive cell line. PD 0332991 (PD) enhances the effects of tamoxifen (Tam) in an MCF7 tamoxifen-insensitive cell line. Dark triangles, PD 0332991 and tamoxifen combination; open squares, PD 0332991 alone; grey diamonds, tamoxifen alone; grey circles, MCF7 parental with tamoxifen alone. Error bars represent the standard error for two separate experiments. The MCF7 parental line is 100% inhibited under these conditions in the presence of tamoxifen (grey circles).

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