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Table 1 Patient demographics

From: Phase I dose escalation pharmacokinetic assessment of intravenous humanized anti-MUC1 antibody AS1402 in patients with advanced breast cancer

Female patients enrolled (n)

26

Age (years) (median/min/max)

55.5/32.0/72.0

Mean weight ± SD (kg) (range)

73.1 ± 14.6 (50-108)

Median months from diagnosis of metastatic disease to study entry (months) (range)

14.4 (1.6-67.2)

WHO performance status (n = 26)

 

   0

17

   1

9

Steroid hormone receptor status (n = 24)

 

   ER and/or PR+

18

   ER and PR-

8

HER2 status a (n = 22)

 

   HER2+

5

   HER2-

17

Metastatic tumor sites (n = 26)

 

   Lung

17

   Bone

15

   Liver

13

   Lymph nodes

12

   Lesions on more than one organ

22

Race (n = 26)

 

   Caucasian

20

   Asian

2

   Hispanic

1

   African-American

3

  1. aHER2 status confirmed by fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC).