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Table 2 Microsatellite markers used for loss of heterozygosity analysis

From: Comparative evaluation of cell-free tumor DNA in blood and disseminated tumor cells in bone marrow of patients with primary breast cancer

Microsatellite
markers
Chromosomal
region
Tumor suppressor gene Function
D3S1255 3p24.2-25 unknown  
D9S171 9p21 P16 (INK4A) Regulator of cell cycle
D10S1765 10q23.3 PTEN
phosphatase and tensin homologue
Regulator of cell growth, metabolism and survival
D13S218 13q12-13 BRCA2
Breast cancer type 2
Regulator of cell cycle
D16S421 16q22-23 E-cadherin Epithelial cell adhesion molecule
D17S855 17q21 BRCA1
Breast cancer type 2
Regulator of cell cycle