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Table 2 Microsatellite markers used for loss of heterozygosity analysis

From: Comparative evaluation of cell-free tumor DNA in blood and disseminated tumor cells in bone marrow of patients with primary breast cancer

Microsatellite

markers

Chromosomal

region

Tumor suppressor gene

Function

D3S1255

3p24.2-25

unknown

 

D9S171

9p21

P16 (INK4A)

Regulator of cell cycle

D10S1765

10q23.3

PTEN

phosphatase and tensin homologue

Regulator of cell growth, metabolism and survival

D13S218

13q12-13

BRCA2

Breast cancer type 2

Regulator of cell cycle

D16S421

16q22-23

E-cadherin

Epithelial cell adhesion molecule

D17S855

17q21

BRCA1

Breast cancer type 2

Regulator of cell cycle