Figure 3
From: An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ
iFish analysis of a DCIS.COM intraductal xenograft. Human-derived DCIS.COM cells are contained within the boundaries of mouse myoepithelial cells and basement membrane. The panels depict immunofluorescence staining of paraffin sections from a fat pad containing DCIS.COM intraductal lesions by using anti-mouse smooth muscle actin antibody (a-c), anti-human pan cytokeratin antibody (d-e), iFish with fluorescently labeled human (green) (f-j), and mouse (red) Cot-1 DNA as probes, and merged images of all panels (p-t).