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Table 1 The features at initial detection of MIN and early invasive cancers

From: Magnetic resonance imaging of the natural history of in situmammary neoplasia in transgenic mice: a pilot study

Feature at initial detection MIN
(n = 21)
Invasive cancers
(n = 14)
Region Upper gland 2 (9%) 1 (7%)
  Mid gland 10 (48%) 8 (57%)
  Lower gland 9 (43%) 5 (36%)
Distance from
lymph node (mm)
  3.5 ± 1.8 6.6 ± 7.6
Age (weeks)   12.7 ± 2.6 16.3 ± 3.2
Volume (mm 3 )   0.34 ± 0.22 17.2 ± 41.6*
Morphology    
Type** Nonmass 21 (100%) 0 (0%)
  Mass 0 (0%) 14 (100%)
Distribution (Nonmass) Ductal 11 (52%) --
  Segmental 9 (43%) --
  Linear 1 (5%) --
Pattern (Nonmass) Clumped 2 (10%) --
  Homogeneous 14 (67%) --
  Stippled 5 (23%) --
Shape (Mass) Irregular -- 3 (21%)
  Round -- 9 (64%)
  Lobular -- 2 (14%)
Margins (Mass) Smooth -- 10 (71%)
  Irregular -- 4 (29%)
Pattern (Mass) Heterogeneous -- 4 (29%)
  Homogeneous -- 10 (71%)
  1. *If we exclude two tumors that initially presented at over 100 mm3, the average was 1.96 ± 2.01 mm3.
  2. ** Please note that by definition 'mass' lesions were classified as invasive tumors, while 'nonmass' lesions were classified as mammary intraepithelial neoplasia (MIN).