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Table 1 The features at initial detection of MIN and early invasive cancers

From: Magnetic resonance imaging of the natural history of in situmammary neoplasia in transgenic mice: a pilot study

Feature at initial detection

MIN

(n = 21)

Invasive cancers

(n = 14)

Region

Upper gland

2 (9%)

1 (7%)

 

Mid gland

10 (48%)

8 (57%)

 

Lower gland

9 (43%)

5 (36%)

Distance from

lymph node (mm)

 

3.5 ± 1.8

6.6 ± 7.6

Age (weeks)

 

12.7 ± 2.6

16.3 ± 3.2

Volume (mm 3 )

 

0.34 ± 0.22

17.2 ± 41.6*

Morphology

   

Type**

Nonmass

21 (100%)

0 (0%)

 

Mass

0 (0%)

14 (100%)

Distribution (Nonmass)

Ductal

11 (52%)

--

 

Segmental

9 (43%)

--

 

Linear

1 (5%)

--

Pattern (Nonmass)

Clumped

2 (10%)

--

 

Homogeneous

14 (67%)

--

 

Stippled

5 (23%)

--

Shape (Mass)

Irregular

--

3 (21%)

 

Round

--

9 (64%)

 

Lobular

--

2 (14%)

Margins (Mass)

Smooth

--

10 (71%)

 

Irregular

--

4 (29%)

Pattern (Mass)

Heterogeneous

--

4 (29%)

 

Homogeneous

--

10 (71%)

  1. *If we exclude two tumors that initially presented at over 100 mm3, the average was 1.96 ± 2.01 mm3.
  2. ** Please note that by definition 'mass' lesions were classified as invasive tumors, while 'nonmass' lesions were classified as mammary intraepithelial neoplasia (MIN).