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Table 1 Univariate association of pathway deregulation with disease-free survival

From: An integration of complementary strategies for gene-expression analysis to reveal novel therapeutic opportunities for breast cancer

Pathway Overall LumA LumB Her2 Basal
Ras 0.64 0.081 0.6 0.75 0.87
Myc 0.0033 0.92 0.0091 0.037 0.7
E2F3 1.8E-04 0.55 0.0044 0.13 0.13
Bcat 0.22 0.43 0.084 0.64 0.56
Src 0.85 0.79 0.29 0.32 0.7
NP63 0.93 0.21 0.83 0.73 0.19
PI3K 0.72 0.12 0.82 0.84 0.15
p53mut 6.0E-06 0.15 0.0014 0.037 0.77
Her1 1.5E-04 0.12 0.077 0.11 0.98
ER 3.9E-04 0.15 0.001 0.083 0.078
Proliferation 3.0E-05 0.088 0.0035 0.046 0.76
  1. P values of the pathway coefficient when predicting disease-free survival (Cox proportional hazard P values). The pathways with significant relapse-free survival associations are indicated in italics; these were tested across all patients, and across all patients within each subtype separately.