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Table 3 Last step of multivariate Cox proportional hazards analysis

From: Presence of HER4 associates with increased sensitivity to Herceptin™ in patients with metastatic breast cancer

Parameter Overall survival
  HR 95% CI P
HER4 IHC 0.38 0.18 to 0.82 0.013
HER4 FISH <0.01 <0.01 to 0.17 0.005
Grading 3.2 1.16 to 8.81 0.024
  1. Overall survival was defined from beginning of Herceptin™ treatment, Cox analysis was performed stepwise backwards.
  2. CI = confidence interval; HR = hazard ratio; FISH = fluorescence in situ hybridisation; HER = human epidermal growth factor receptor; IHC = immunohistochemistry.