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Table 3 Last step of multivariate Cox proportional hazards analysis

From: Presence of HER4 associates with increased sensitivity to Herceptin™ in patients with metastatic breast cancer

Parameter

Overall survival

 

HR

95% CI

P

HER4 IHC

0.38

0.18 to 0.82

0.013

HER4 FISH

<0.01

<0.01 to 0.17

0.005

Grading

3.2

1.16 to 8.81

0.024

  1. Overall survival was defined from beginning of Herceptin™ treatment, Cox analysis was performed stepwise backwards.
  2. CI = confidence interval; HR = hazard ratio; FISH = fluorescence in situ hybridisation; HER = human epidermal growth factor receptor; IHC = immunohistochemistry.